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May 17, 2012

Blood Viscosity: The Unifying Parameter In Cardiovascular Disease Risk

By Ralph E. Holsworth, Jr., DO & Jonathan V. Wright, MD - Vol. 13, No. 1. Spring, 2012

A quick search on the PubMed database reveals nearly 1,000 scientific papers linking blood viscosity to cardiovascular disease events and risk factors.

In fact, incBloodViscosityreased blood viscosity is the only biological parameter that has been linked with all of the other major cardiovascular risk factors, including high blood pressure, elevated LDL cholesterol, low HDL, type-II diabetes, metabolic syndrome, obesity, smoking, age, and male gender.

This led to the proposition, which is becoming more widely accepted, that blood viscosity is the unifying parameter for CVD. Increased viscosity may be the reason why the other biochemical, metabolic and demographic factors are important, and provides the underlying mechanism through which these other factors convey the pre-inflammatory insult to the arterial walls (Sloop GD. Med Hypotheses 1996; 47:321-5).

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