Delta-Tocotrienol Reverses Metabolic Syndrome, Fatty Liver

By Janet Gulland, Contributing Writer

AnnattoTwice daily supplementation with δ-tocotrienol, one of the eight isoforms of vitamin E, produced marked reductions of body mass index, triglyceride levels, markers of inflammation, alanine transaminase (ALT) and aspartate transaminase (AST) in a cohort of overweight patients with metabolic syndrome and non-alcoholic fatty liver disease (NAFLD).

The data, from a 71-patient placebo-controlled study, suggest that δ-tocotrienol has a great potential role to play in the management of these increasingly common and co-occurring conditions.

Dr. Muhammad Amjad Pervez and colleagues at the National University of Medical Sciences, Islamabad, Pakistan, randomized the 71 patients—all of whom were overweight or obese, with the characteristics of metabolic syndrome, and ultrasound-confirmed NAFLD—to twice-daily treatment with either 300 mg δ-tocotrienol (total of 600 mg/day) or identically matched placebo capsules.

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Featured Articles

The Roots of Supplement Quality Are in the Soil

Written by Kristen Schepker, Assistant Editor

For dietary supplements containing plant-derived ingredients, product quality has its roots in the soil in which those plants are grown. Recent developments in soil science and sustainable agriculture are helping conscientious companies to safeguard product quality in an era of widespread environmental degradation.

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A Guide to the Endocannabinoid System

Written by Jamie Corroon, ND, MPH & Jake Felice, ND

Interest in the medical use of phytocannabinoids from Cannabis Sativa L. (Cannabis) has reached an all-time high. These exogenous, plant-derived ligands interact with endogenously produced proteins, receptors, enzymes and endogenous ligands, in one of the most evolutionarily preserved biological systems known to the life sciences: the endogenous cannabinoid signaling system, better known as the endocannabinoid system (ECS).

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HPC Video

Joe Pizzorno - The Toxin Solution

Written by Meg Sinclair

For decades, Dr. Pizzorno has been at the forefront of a movement to build bridges between naturopathic, functional, and mainstream medicine. In recent years, his attention has been focused on the myriad ways that environmental toxins are damaging personal and public health, and on developing practical strategies to help people reduce their toxic loads.

His recent book, The Toxin Solution, presents a harrowing picture yet offers good clinical guidance on how to manage the onslaught. Consider the following:

•    94% of Americans are exposed to enough polycyclic aromatic hydrocarbons to double their lifetime risk of asthma.
•    60% of US women carry loads of PCB187 sufficient to double their risk of breast cancer.
•    33% of Americans have lead levels high enough to double the risk of Amyotrophic Lateral Sclerosis (ALS).
•    25% are exposed to enough aluminum to double Alzheimer’s risk.

Holistic Primary Care had the honor of hosting Dr. Pizzorno at our 2017 Practitioner Channel Forum. He shared his research on the role of common toxins in chronic disease and his field-tested therapeutic strategies. Watch the full-length session from HPC’s video archive:

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