The optimally healthy human gut should contain between 20,000 and 30,000 species of bacteria. Variety is key. The greater the diversity, the healthier the microbiome. Zealous use of probiotics, while reflecting a positive trend overall, could be causing problems by "monocropping" the GI tract with a relatively small number of species at the expense of ecosystem diversity.
When making dietary choices, a food’s potential benefits to the gut should be a key part of the decision, urged Tom O’Bryan, DC, at Holistic Primary Care’s 7th annual Heal Thy Practice conference.
Zonulin, an endogenous protein that regulates the size of intestinal tight junctions, could be useful as a serum marker for non-celiac gluten sensitivity—a condition that has been the subject of much controversy in recent years.
New research published recently in Clinical Gastroenterology and Hepatology provides strong evidence that psychological factors need to be brought back into the clinical picture of peptic ulcer disease.
Women may be three times more likely to develop Crohn's disease if they have used oral contraceptive pills for five years or more, according to data from a Harvard University study.
Disturbance of the gut microbiome, also known as dysbiosis, has a major detrimental effect on human health. As microbiome research continues to explode worldwide, we are learning that microbial dysregulation within the gut is an important contributing factor in a wide range of common disorders.
It's "the greatest turnaround in science and medicine in the last 150 years," says Raphael Kellman, MD, of the current microbiome revolution.
As many as one-third of all patients with inflammatory bowel disease (IBD) have iron-deficiency anemia (IDA), and primary care clinicians can play a key role in identifying and remedying this common but often overlooked comorbidity.
Two new studies indicate that adding oral probiotics to the therapeutic mix boosts the efficacy of conventional drug protocols in eradicating Helicobacter pylori, the most common bacterial pathogen worldwide, and a main driver of peptic ulcers.
Peppermint can help take some of the “irritable” out of Irritable Bowel Syndrome, according to a recent metanalysis of 9 randomized trials.